Selected publications
Yu, Y.B., Kuwana, R. (2026) Enhancing Medicine Safety Through Patient Empowerment. Pharm. Res.
Briggs, K.T et al., (2026) Multiplatform benchtop NMR interlaboratory study of model liquid dosage forms of pharmaceutical products. Anal. Chem. 98, 1451-1459. https://pubs.acs.org/doi/10.1021/acs.analchem.5c05487
Biswas, P.G., Taraban, M.B., Briggs, K.T., Yu, Y.B. (2025) Quantifying hydrogen populations in liquid mixtures using 1H NMR relaxometry. Anal. Chem. 97, 19128-19135. https://pubs.acs.org/doi/10.1021/acs.analchem.5c02606
Taraban, M.B., Briggs, K.T., Grunin, L., Yu, Y.B. (2025) Advancing pharmaceutical security: noninvasive detection of falsified vaccines and drugs using wNMR Pharm. Res. 42, 981-1001. https://link.springer.com/article/10.1007/s11095-025-03880-w
Briggs, K.T., Taraban, M.B., Yu, Y.B. (2024) Using water proton NMR to characterize aluminum-adjuvanted vaccines. Chapter 5 in “Magnetic Resonance and its Applications in Drug Formulation and Delivery; New Developments in NMR”, p. 213-243, M. Mantle, L. Hughes (Editors), Royal Society of Chemistry. ISBN: 978-1-78801-740-4 DOI: https://doi.org/10.1039/9781788019996
Song, J., Taraban, M.B., Yu, Y.B., Lu, L., Biswas, P.G., Xu, W., Xi, H., Bhambhani, A., Hu, G., Su, Y. (2024) In-situ biophysical characterization of high concentration protein formulations using wNMR. mAbs, 16(1), 2304624. https://www.tandfonline.com/doi/full/10.1080/19420862.2024.2304624?src=exp-la
Yu, Y.B., Briggs, K.T. & Taraban, M.B. (2023) Preventive Pharmacovigilance: timely and precise prevention of adverse events through person-level patient screening and dose-level product surveillance. Pharm. Res. 40, 2103-2106. https://doi.org/10.1007/s11095-023-03548-3
Taraban, M.B., Ndung’u, T., Karki, P. et al. (2023) Analysis of the Adsorbed Vaccine Formulations Using Water Proton Nuclear Magnetic Resonance—Comparison with Optical Analytics. Pharm. Res. 40, 1989-1998. https://doi.org/10.1007/s11095-023-03528-7
Briggs, K.T., Taraban, M.B., Yu, Y.B. (2023) Sedimentation behavior of quality and freeze-damaged aluminum-adjuvanted vaccines by wNMR. Human Vaccines & Immunotherapeutics, 19(2), 2215152. https://doi.org/10.1080/21645515.2023.2215152
Taraban, M.B., Briggs, K.T., Yu, Y.B., Jones, M.T., Rosner, L., Bhambhani, A., Williams, D.M., Farrell, C., Reibarkh, M., Su, Y. (2023) Assessing antigen-adjuvant complex stability against physical stresses by wNMR. Pharm. Res. 40, 1435-1446. https://link.springer.com/article/10.1007/s11095-022-03437-1
Solomon, T.L., Delaglio, F., Giddens, J.P., Marino, J.P., Yu, Y.B., Taraban, M.B., Brinson, R.G. (2023) Correlated analytical and functional evaluation of higher order structure perturbations from oxidation of NISTmAb. mAbs, 15, 2160227. https://doi.org/10.1080/19420862.2022.2160227
Yu, Y.B., Briggs, K.T., Taraban, M.B. (2022) Why some people tolerate the second dose of a vaccine but not the first dose. Annals Allergy Asthma Immunol. 128, 477-478. https://www.annallergy.org/article/S1081-1206(22)00079-5/pdf
Taraban MB, Wang Y, Briggs KT, Yu YB. (2022) Inspecting Insulin Products Using Water Proton NMR. I. Noninvasive vs Invasive Inspection. J Diabetes Sci Technol. 16(6), 1410-1418. https://doi.org/10.1177/19322968211023806
Yu, Y.B., Briggs, K.T., Taraban, M.B. (2021) wNMR — an emerging analytical technology: from biomanufacturing to point-of-care. Bioprocess Online, published on Dec. 29, 2021. https://www.bioprocessonline.com/doc/wnmr-an-emerging-analytical-technology-from-biomanufacturing-to-point-of-care-0001
Yu, Y.B., Briggs, K.T., Taraban, M.B., Brinson, R.G., Marino, J.P. (2021) Excipient Innovation through Precompetitive Research. Pharm. Res. 38, 2179-2184. https://link.springer.com/article/10.1007/s11095-021-03157-y
Taraban, M.B, Jones, M.T., Yu, Y.B. (2021) Rapid and noninvasive quantification of capsid gene filling level using water proton nuclear magnetic resonance. Anal. Chem. 93, 15816-15820. https://doi.org/10.1021/acs.analchem.1c04088
Yu, Y.B., Taraban, M.B., Briggs, K.T. (2021) All vials are not the same: Potential role of vaccine quality in vaccine adverse reactions. Vaccine, 39, 6565-6569. https://doi.org/10.1016/j.vaccine.2021.09.065
Yu, Y.B., Briggs, K.T., Taraban, M.B., Brinson, G.B., Marino, J.P. (2021) Grand challenges in pharmaceutical research series: Ridding the cold chain for biologics. Pharm. Res. 38, 3-7. https://link.springer.com/article/10.1007/s11095-021-03008-w
Briggs, K.T., Taraban, M.B., Yu, Y.B. (2020) Quality assurance at the point-of-care: Noninvasively detecting vaccine freezing variability using water proton NMR. Vaccine, 38, 4853-4860. https://www.sciencedirect.com/science/article/abs/pii/S0264410X20306940
Briggs, K.T., Taraban, M.B., Wang, W., Yu, Y.B. (2019) Nondestructive Quantitative Inspection of Drug Products Using Benchtop NMR Relaxometry—the Case of NovoMix® 30. AAPS PharmSciTech 20, 189 https://doi.org/10.1208/s12249-019-1405-0
Taraban, M.B., Briggs, K.T., Merkel, P., Yu, Y.B. (2019) Flow Water Proton NMR: In-Line Process Analytical Technology for Continuous Biomanufacturing. Anal. Chem. 91, 13538-13546. https://pubs.acs.org/doi/10.1021/acs.analchem.9b02622
Briggs, K.T., Taraban, M.B., Yu, Y.B., (2018) Water proton NMR detection of amide hydrolysis and diglycine dimerization. Chem. Commun. 54, 7003-7006. https://pubs.rsc.org/en/content/articlelanding/2018/cc/c8cc03935f
Taraban, M.B., DePaz, R.A., Lobo, B., Yu, Y.B. (2017) Water proton NMR: a tool for protein aggregation characterization. Anal. Chem. 89, 5494-5502. https://pubs.acs.org/doi/10.1021/acs.analchem.7b00464
Taraban, M.B., Li, Y., Joyner, K.A., Stains, J.P., Yu, Y.B. (2016) Impact of matrix dynamic properties on stem cell viability. In: “In Situ Regeneration Medicine”, Lee, S.J., Yoo, J.J., Atala, A. (eds.), Elsevier, Amsterdam, p. 203-214. https://www.sciencedirect.com/science/article/abs/pii/B9780128022252000118
Feng, Y., Taraban, M.B., Yu, Y.B. (2015) Water proton NMR – a sensitive probe for solute association. Chem. Comm. 51, 6804-6807. https://pubs.rsc.org/en/content/articlelanding/2015/cc/c5cc00741k
Feng, Y., Taraban, M.B., Yu, Y.B. (2014) Linear dependence of water proton transverse relaxation rate on the shear modulus of hydrogels. Chem. Comm. 50, 12120-12122.
Hyland, L.L., Taraban, M.B., Yu, Y.B. (2013) Using small-angle scattering techniques to understand mechanical properties of biopolymer-based biomaterials. Soft Matter, 9, 10218-10228.
Yue, X., Taraban, M.B., Hyland, L.L., Yu, Y.B. (2012) Avoiding steric congestion in dendrimer growth through proportionate branching: a twist on da Vinci’s rule of tree branching. J. Org. Chem. 77, 8879-8887.
Jiang, Z.-X., Feng, Y., Yu, Y.B. (2011) Fluorinated paramagnetic chelates as potential multi-chromic 19F tracer agents. Chem. Comm. 47, 7233-7235.
Jiang, Z.-X., Yu, Y.B. (2010) Fluorous mixture synthesis of asymmetric dendrimers. J. Org. Chem. 75, 2044 – 2049.
Jiang, Z.-X., Liu, X., Jeong, E.K., Yu, Y.B. (2009) Symmetry-guided design and fluorous synthesis of a stable and rapidly excreted imaging tracer for 19F MRI. Angew. Chem. Int. Ed. 48, 4755-4758.
Sofou, S., Yu, Y.B. (2008) Delivery systems for the targeted radiotherapy of cancer. Adv. Drug Del. Rev. 60, 1317-1318.
Jiang, Z-X., Yu, Y.B. (2007) The synthesis of a geminally perfluoro-tert-butylated β-amino acid and its protected forms as potential pharmacokinetic modulator and reporter for peptide-based pharmaceuticals. J. Org. Chem. 72, 1464-1467.
Yu, Y.B. (2006) Fluorocarbon nanoparticles as multifunctional drug delivery vehicles. J. Drug Targeting, 14, 663-669.
Ramachandran, S., Flynn, P., Tseng, Y., Yu, Y.B. (2005). Electrostatically-controlled hydrogelation of oligopeptides and protein entrapment. Chem. Mater. 17, 6583-6588.
Wang, W., Yu, Y.B. (2004) Algorithmic generation of freely jointed hard sphere chains and properties of their inertial tensor. J. Biomol. Struct. Dynam. 21, 805-811.
Yu, Y.B. (2003) Comment on “Computational studies of enzyme-catalyzed reactions: where are we in predicting mechanisms and in understanding the nature of enzyme catalysis”. J. Phys. Chem. B, 107, 1721.
Yu, Y. B. (2002) Coiled-coils: stability, specificity, and drug delivery potentials. Adv. Drug Del. Rev. 54, 1113-1129.
Yu, Y.B., Privalov, P.L., Hodges, R.S. (2001) Contribution of translational and rotational motions to molecular association in aqueous solution. Biophys. J. 81, 1632-1642.
Yu, Y.B., Wagschal, K.C., Mant, C.T., Hodges, R.S. (2000) Trapping the monomeric alpha-helical state during the unfolding of coiled-coils by reversed–phase liquid chromatography. J. Chromatogr. A, 890, 81-94.
Yu, Y.B., Lavigne, P., Privalov, P.L., Hodges, R.S. (1999) The measure of interior disorder in a folded protein and its contribution to stability. J. Am. Chem. Soc. 121, 8443-8449.