Selected publications

Song, J., Taraban, M.B., Yu, Y.B., Lu, L., Biswas, P.G., Xu, W., Xi, H., Bhambhani, A., Hu, G., Su, Y. (2024) In-situ biophysical characterization of high concentration protein formulations using wNMR.  mAbs, 16(1), 2304624. https://www.tandfonline.com/doi/full/10.1080/19420862.2024.2304624?src=exp-la

Yu, Y.B., Briggs, K.T. & Taraban, M.B. (2023) Preventive Pharmacovigilance: timely and precise prevention of adverse events through person-level patient screening and dose-level product surveillance. Pharm. Res. 40, 2103-2106. https://doi.org/10.1007/s11095-023-03548-3

Taraban, M.B., Ndung’u, T., Karki, P. et al. (2023) Analysis of the Adsorbed Vaccine Formulations Using Water Proton Nuclear Magnetic Resonance—Comparison with Optical Analytics. Pharm. Res. 40, 1989-1998. https://doi.org/10.1007/s11095-023-03528-7

Briggs, K.T., Taraban, M.B., Yu, Y.B. (2023) Sedimentation behavior of quality and freeze-damaged aluminum-adjuvanted vaccines by wNMR.  Human Vaccines & Immunotherapeutics, 19(2), 2215152.  https://doi.org/10.1080/21645515.2023.2215152

Taraban, M.B., Briggs, K.T., Yu, Y.B., Jones, M.T., Rosner, L., Bhambhani, A., Williams, D.M., Farrell, C., Reibarkh, M., Su, Y. (2023) Assessing antigen-adjuvant complex stability against physical stresses by wNMR. Pharm. Res. 40, 1435-1446.

Solomon, T.L., Delaglio, F., Giddens, J.P., Marino, J.P., Yu, Y.B., Taraban, M.B., Brinson, R.G. (2023) Correlated analytical and functional evaluation of higher order structure perturbations from oxidation of NISTmAb. mAbs, 15, 2160227.  https://doi.org/10.1080/19420862.2022.2160227

Yu, Y.B., Briggs, K.T., Taraban, M.B. (2022) Why some people tolerate the second dose of a vaccine but not the first dose.  Annals Allergy Asthma Immunol. 128, 477-478.

Yu, Y.B., Briggs, K.T., Taraban, M.B. (2021) wNMR — an emerging analytical technology: from biomanufacturing to point-of-care. Bioprocess Online, published on Dec. 29, 2021.  https://www.bioprocessonline.com/doc/wnmr-an-emerging-analytical-technology-from-biomanufacturing-to-point-of-care-0001

Yu, Y.B., Briggs, K.T., Taraban, M.B., Brinson, R.G., Marino, J.P. (2021) Excipient Innovation through Precompetitive Research.  Pharm. Res. 38, 2179-2184.

Taraban, M.B, Jones, M.T., Yu, Y.B. (2021) Rapid and noninvasive quantification of capsid gene filling level using water proton nuclear magnetic resonance.  Anal. Chem. 93, 15816-15820.  https://doi.org/10.1021/acs.analchem.1c04088

Yu, Y.B., Taraban, M.B., Briggs, K.T. (2021) All vials are not the same: Potential role of vaccine quality in vaccine adverse reactions. Vaccine,  39, 6565-6569.  https://doi.org/10.1016/j.vaccine.2021.09.065

Yu, Y.B., Briggs, K.T., Taraban, M.B., Brinson, G.B., Marino, J.P. (2021) Grand challenges in pharmaceutical research series: Ridding the cold chain for biologics.  Pharm. Res. 38, 3-7.

Briggs, K.T., Taraban, M.B., Yu, Y.B. (2020) Quality assurance at the point-of-care: Noninvasively detecting vaccine freezing variability using water proton NMR.  Vaccine, 38, 4853-4860.

Taraban, M.B., Briggs, K.T., Merkel, P., Yu, Y.B. (2019) Flow Water Proton NMR: In-Line Process Analytical Technology for Continuous Biomanufacturing.  Anal. Chem. 91, 13538-13546.

Briggs, K.T., Taraban, M.B., Yu, Y.B., (2018) Water proton NMR detection of amide hydrolysis and diglycine dimerization.  Chem. Commun. 54, 7003-7006.

Taraban, M.B., DePaz, R.A., Lobo, B., Yu, Y.B. (2017) Water proton NMR: a tool for protein aggregation characterization.  Anal. Chem. 89, 5494-5502.

Read More

Taraban, M.B., Li, Y., Joyner, K.A., Stains, J.P., Yu, Y.B. (2016) Impact of matrix dynamic properties on stem cell viability.  In: “In Situ Regeneration Medicine”, Lee, S.J., Yoo, J.J., Atala, A. (eds.), Elsevier, Amsterdam, p. 203-214.Feng, Y., Taraban, M.B., Yu, Y.B. (2015) Water proton NMR – a sensitive probe for solute association.  Chem. Comm. 51, 6804-6807.

Feng, Y., Taraban, M.B., Yu, Y.B. (2014) Linear dependence of water proton transverse relaxation rate on the shear modulus of hydrogels.   Chem. Comm. 50, 12120-12122.

Hyland, L.L., Taraban, M.B., Yu, Y.B. (2013) Using small-angle scattering techniques to understand mechanical properties of biopolymer-based biomaterials.  Soft Matter, 9, 10218-10228.

Yue, X., Taraban, M.B., Hyland, L.L., Yu, Y.B. (2012) Avoiding steric congestion in dendrimer growth through proportionate branching: a twist on da Vinci’s rule of tree branching.  J. Org. Chem. 77, 8879-8887.

Jiang, Z.-X., Feng, Y., Yu, Y.B. (2011) Fluorinated paramagnetic chelates as potential multi-chromic 19F tracer agents.  Chem. Comm. 47, 7233-7235.

Jiang, Z.-X., Yu, Y.B. (2010) Fluorous mixture synthesis of asymmetric dendrimers.  J. Org. Chem. 75, 2044 – 2049.

Jiang, Z.-X., Liu, X., Jeong, E.K., Yu, Y.B. (2009) Symmetry-guided design and fluorous synthesis of a stable and      rapidly excreted imaging tracer for 19F MRI.  Angew. Chem. Int. Ed. 48, 4755-4758.

Sofou, S., Yu, Y.B. (2008) Delivery systems for the targeted radiotherapy of cancer.  Adv. Drug Del. Rev. 60, 1317-1318.

Jiang, Z-X., Yu, Y.B. (2007) The synthesis of a geminally perfluoro-tert-butylated β-amino acid and its protected forms as potential pharmacokinetic modulator and reporter for peptide-based pharmaceuticals. J. Org. Chem. 72, 1464-1467.

Yu, Y.B. (2006) Fluorocarbon nanoparticles as multifunctional drug delivery vehicles.  J. Drug Targeting, 14, 663-669.

Ramachandran, S., Flynn, P., Tseng, Y., Yu, Y.B. (2005).  Electrostatically-controlled hydrogelation of oligopeptides and protein entrapment.  Chem. Mater. 17, 6583-6588.

Wang, W., Yu, Y.B. (2004) Algorithmic generation of freely jointed hard sphere chains and properties of their inertial tensor.  J. Biomol. Struct. Dynam. 21, 805-811.

Yu, Y.B. (2003) Comment on “Computational studies of enzyme-catalyzed reactions: where are we in predicting mechanisms and in understanding the nature of enzyme catalysis”. J. Phys. Chem. B, 107, 1721.

Yu, Y. B.  (2002) Coiled-coils: stability, specificity, and drug delivery potentials.  Adv. Drug Del. Rev. 54, 1113-1129.

Yu, Y.B., Privalov, P.L., Hodges, R.S. (2001) Contribution of translational and rotational motions to molecular association in aqueous solution. Biophys. J. 81, 1632-1642.

Yu, Y.B., Wagschal, K.C., Mant, C.T., Hodges, R.S. (2000) Trapping the monomeric alpha-helical state during the unfolding of coiled-coils by reversed–phase liquid chromatography.  J. Chromatogr. A, 890, 81-94.

Yu, Y.B., Lavigne, P., Privalov, P.L., Hodges, R.S.  (1999) The measure of interior disorder in a folded protein and its contribution to stability.  J. Am. Chem. Soc. 121, 8443-8449.

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