Dr. Jace Jones is a research assistant professor in the Department of Pharmaceutical Sciences (PSC) and associate director of the Mass Spectrometry Center at the University of Maryland School of Pharmacy.
About Dr. Jones:
My current appointment involves a joint position as a research assistant professor and associate director of the Mass Spectrometry Center in the Department of Pharmaceutical Sciences at the University of Maryland School of Pharmacy. Prior to transitioning back to academia, I was the technical director at Jones Environmental, Inc. in Fullerton, Calif. I earned my doctorate in analytical chemistry at the University of Washington, Seattle under the direction of František Tureček. My undergraduate degree (BS in biology with a minor in chemistry) was obtained at Whitworth University in Spokane, Wash.
My research at the University of Maryland School of Pharmacy focuses on the development of mass spectrometry-based platforms that couple biomarker discovery to quantitative validation from circulating and tissue metabolites. The overarching goal of these endeavors, broadly classified as metabolomics, is to produce a panel of circulating (e.g., plasma) metabolite biomarkers that are organ specific. In addition, our strategy has been to delineate metabolite biomarkers as prognostic or diagnostic. In other words, we seek to ascertain the distinction between biomarkers that are predictive (prognostic biomarker) or reflective (diagnostic biomarker) of the disease/injury. In either case, whether the biomarker is predictive or reflective, another primary output of a validated biomarker is its potential insight into mechanism of action. Greater understanding of a disease/injury’s mechanism of action paves the way for potential therapeutic intervention and possible drug development targets. Furthermore, the incorporation of validated biomarkers provides a robust quantitative assessment of drug efficacy and substantiates trigger-to-treat standardization protocols.
Jace W. Jones, PhD
Research Assistant Professor
Associate Director, Mass Spectrometry Center
Department of Pharmaceutical Sciences
University of Maryland School of Pharmacy
20 N. Pine Street, Room N721
Baltimore, MD 21201
Phone: (410) 706-7598
Fax: (410) 706-0886