Peter Doshi, PhD, is an associate professor of pharmaceutical health services research.
Peter Doshi, PhD, is an associate professor of pharmaceutical health services research at the University of Maryland School of Pharmacy and senior editor at The BMJ. His research focuses on the drug approval process, how the risks and benefits of medical products are communicated, and improving the credibility and accuracy of evidence synthesis and biomedical publications.
Doshi campaigns for greater transparency of clinical trial data and has received wide recognition for his work. In 2013, the New York Times reported on Doshi’s work to increase public access to clinical study reports. The same year he was also chosen for The Wired “Smart List.” In 2015, he received a New Investigator Award from the American Association of Colleges of Pharmacy. Doshi has presented on the topic of clinical trial data sharing to the Institute of Medicine in 2013 and 2014, and served on advisory panels to the European Medicines Agency regarding its policy on proactive publication of clinical trial data.
Much of Doshi’s research has examined the science and politics of influenza policy. His most cited publication is a Cochrane systematic review of neuraminidase inhibitors for influenza. This review—the first Cochrane review to be based exclusively on clinical study reports and other regulatory documents—challenged previous understandings of the drugs’ effectiveness and raised new questions about their safety, and led to governmental inquiries in the United Kingdom. It is cited as a milestone in the James Lind Library, which chronicles the evolution of fair tests and research synthesis.
Doshi leads the RIAT Support Center, funded by the Laura and John Arnold Foundation. The Restoring Invisible and Abandoned Trials (RIAT) initiative enables researchers everywhere to address two long-standing problems in the biomedical literature: non-publication and misreporting of trials. The RIAT Support Center aims to accelerate the correction of the scientific record of clinical trials by making publications more accurate and more complete, addressing these problems of publication bias and reporting bias.
Doshi earned an A.B. in anthropology from Brown University, an A.M. in East Asian Studies from Harvard University and Ph.D. in history, anthropology, and science, technology and society from MIT. During his PhD, he was an intern at the Japanese Ministry of Health, Labour and Welfare, a research student at the National Institute of Infectious Diseases, Tokyo, and studied as visiting researcher at the University of Tokyo Center for Biomedical Ethics and Law. Doshi completed a fellowship in comparative effectiveness research at Johns Hopkins before joining the faculty at the University of Maryland School of Pharmacy.
Between 2011 and 2014, Doshi was a co-recipient of a UK National Institute for Health Research grant to carry out a Cochrane review of neuraminidase inhibitors (PI: Carl Heneghan, University of Oxford). In 2015, Doshi received a New Investigator Award from the American Association of Colleges of Pharmacy to fund a PhD student to study consumer medical information about the possible harms of statins (PI: Peter Doshi). From 2015 to 2016, Doshi was a co-investigator on a Patient-Centered Outcomes Research Institute funded grant to compare data from multiple sources (PI: Kay Dickersin, Johns Hopkins University). From 2015 to 2018, Doshi has been a co-investigator in a Cochrane Methods Innovation Fund sponsored project to develop guidance regarding when to use regulatory data in Cochrane reviews (PI: Tom Jefferson). Beginning in 2018, Doshi will be a collaborator on a Canadian Institutes of Health Research funded project “Beyond Transparency in Pharmaceutical Research and Regulation” (PI: Matthew Herder, Dalhousie University, 2018-2022). Doshi is principal investigator of the RIAT Support Center, which is funded by the Laura and John Arnold Foundation (2017-2021).
Please visit the BMJ editorial staff website for a statement of competing interests.
Writing/speaking on Covid-19:
- “Incorrect Statement” (comment posted on jama.com, Mar 2, 2021)
- Public statement at FDA VRBPAC advisory committee meeting to discuss Janssen’s EUA application, Feb 26, 2021 (video begins at 4:46:40; script)
- “Transparency & Covid-19 vaccines.” 8 minute talk in The BMJ’s Known Unknown webinar series (Feb 25, 2021)
- “How to Fix the Coronavirus Vaccine Rollout: Don’t Pressure the Vaccine-Hesitant.” (New York Times, Jan 7, 2021)
- “Pfizer and Moderna’s “95% effective” vaccines—we need more details and the raw data” (BMJ Opinion, Jan 4, 2021)
- “Did the FDA understaff its review of the Pfizer/BioNTech vaccine?” (Stat News, Dec 17, 2020)
- “How to Expand Access to COVID Vaccines without Compromising the Science” (Scientific American, Dec 17, 2020)
- “Let’s be cautious and first see the full data” (Public statement at FDA VRBPAC advisory committee meeting to discuss Pfizer’s EUA application, Dec 10, 2020; slides and script)
- “Determining the infectious potential of individuals with positive RT-PCR SARS-CoV-2 tests” (Clinical Infectious Diseases, Dec 4, 2020)
- “Pfizer and Moderna’s ‘95% effective’ vaccines—let’s be cautious and first see the full data” (BMJ Opinion, Nov 26, 2020)
- “Covid-19 Vaccine Trials” (Public statement at FDA advisory committee (VRBPAC) meeting, Oct 22, 2022; video begins at 5:21:23, and slides)
- “Will covid-19 vaccines save lives? Current trials aren’t designed to tell us” (The BMJ, Oct 21, 2020)
- “Covid-19 vaccine trial protocols released” (The BMJ, Oct 21, 2020)
- “How clinically serious is SARS-CoV-2 infection for children and young adults?” (Rapid response on bmj.com, Oct 12, 2020)
- “Are We Testing Coronavirus Vaccines the Right Way?” (New York Times, Sept 22, 2020)
- “Covid-19: Do many people have pre-existing immunity?” (The BMJ, Sept 17, 2020)
- “Covid-19: Should doctors recommend treatments and vaccines when full data are not publicly available?” (The BMJ, Aug 24, 2020)
Many of Doshi’s publications are available for free through special links listed on the University of Maryland, Baltimore’s Digital Archive. (To access the free, full-text, look for the “External Resource/s: Full Text” link on each article’s individual webpage.)
- Doshi P, Dickersin K, Healy D, Vedula SS, Jefferson T. Restoring invisible and abandoned trials: a call for people to publish the findings. BMJ. 2013 Jun 13;346:f2865. doi:10.1136/bmj.f2865 (Free full text)
- Doshi P, Jefferson T, Del Mar C. The imperative to share clinical study reports: recommendations from the tamiflu experience. PLoS Med. 2012 Apr 10;9(4):e1001201. doi:10.1371/journal.pmed.1001201 (Free full text)
- Doshi P, Goodman SN, Ioannidis JPA. Raw data from clinical trials: within reach? Trends in Pharmacological Sciences 2013;34(12):645-647. doi:10.1016/j.tips.2013.10.006
- Persaud N, Doshi P. North American regulatory agencies can and should make clinical trial data publicly available. Canadian Medical Association Journal. 2015 Oct 13;188(2):96-7. doi:10.1503/cmaj.150679
- Doshi P. Influenza vaccines: Time for a rethink. JAMA Intern Med. 2013 Mar 18;173(11):1014-1016. doi:10.1001/jamainternmed.2013.490
- Doshi P. 2008. Trends in recorded influenza mortality: United States, 1900-2004. Am J Public Health. 98(5):939-945. doi:10.2105/AJPH.2007.119933
- Jefferson T, Jones M, Doshi P, Spencer EA, Onakpoya I, Heneghan CJ. Oseltamivir for influenza in adults and children: systematic review of clinical study reports and summary of regulatory comments. BMJ. 2014 Apr 9;348:g2545. doi:10.1136/bmj.g2545 (Free full text; also see full Cochrane Review)
- Doshi P, Jefferson T. Clinical study reports of randomised controlled trials: an exploratory review of previously confidential industry reports. BMJ Open. 2013 Feb 26;3(2):e002496. doi:10.1136/bmjopen-2012-002496 (Free full text)
- Hung A, Sieluk J, Doshi P. The Untapped Potential of Pharmacy Leaflets for Informing Patients About Drug Benefits and Risks. JAMA Intern Med. 2016 Jan;176(1):11-2. doi: 10.1001/jamainternmed.2015.6656.
- Sieluk J, Palasik B, dosReis S, Doshi P. ADHD medications and cardiovascular adverse events in children and adolescents: cross-national comparison of risk communication in drug labeling. Pharmacoepidemiol Drug Saf. 2017 Mar;26(3):274-284. doi:10.1002/pds.4164
- Doshi P. Influenza: marketing vaccine by marketing disease. BMJ. 2013;346:f3037. doi:10.1136/bmj.f3037 (Free full text)
- Doshi P, Hur P, Jones M, Albarmawi H, Jefferson T, Morgan DJ, et al. Informed Consent to Study Purpose in Randomized Clinical Trials of Antibiotics, 1991 Through 2011. JAMA Intern Med. 2017 Oct 1;177(10):1452-1459. doi:10.1001/jamainternmed.2017.3820
Selected Op-Eds and Blog Posts
- Doshi P, Jefferson T. 2012. Drug data shouldn’t be secret. New York Times op-ed
- Doshi P, Mandl K, Bourgeois F. 2016. Tamiflu For All? Evidence Of Morbidity In CDC’s Antiviral Guidelines. Health Affairs Blog
- Doshi P. 2017. Speed vs safety in the FDA’s new drug approvals—speed wins, again. BMJ Opinion
- Doshi P. 2020. Are We Testing Coronavirus Vaccines the Right Way? New York Times op-ed
- Doshi P. 2020. How to Fix the Coronavirus Vaccine Rollout: Don’t Pressure the Vaccine-Hesitant. New York Times op-ed
Selected Video and News Features
- PBS NewsHour (2018). Does Tamiflu work? We asked a scientist
- CBS Evening News (2014). Government stockpiles flu medicine, but does it work?
- New York Times (2013). Breaking the Seal on Drug Research
- Doshi (2012) 15 minutes on Lessons from the Tamiflu experience
Department of Pharmaceutical Health Services Research
220 Arch Street
Floor 12, Room 01-228
Baltimore, MD 21201
Phone: +1 410 706 0527
Fax: +1 410 706 5394