Publications

Dr. Heavner has published in her areas of expertise, as listed below:

Students, residents, and fellows under supervision are indicated with an asterisk*

Publications in Refereed/Peer Reviewed Journals

  • Smith ZR, Palm NM, Smith SE, Dixit D, Keats K, Ciapala SR, Tran T, Newsome AS, Heavner MS. Critical care pharmacist perspectives on optimal practice models and prioritization of professional activities: A cross-sectional survey. Am J Health Syst Pharm. 2024; Online ahead of print. [Original Research]. Citations: 0
  • Heavner MS. Next generation of critical care pharmacist practice studies: Beyond essential. Am J Health Syst Pharm. 2024; Online ahead of print. https://academic.oup.com/ajhp/advance-article-abstract/doi/10.1093/ajhp/zxae146/7683015?utm_source=advanceaccess&utm_campaign=ajhp&utm_medium=email [Invited Commentary]. Citations: 0
  • Rinehart MC*, Ghorashi S*, Heavner MS, Tata A, Bathula M, Kelly S, Yeung SYA, Landolf K, So JY, Goel N, Grover BE. An assessment of sleep aid and sleep promotion practices in hospitalized medical patients. J Am Pharm Assoc. 2024; Online ahead of print. https://doi.org/10.1016/j.japh.2024.102042 [Original Research]. Citations: 0
  • Keats K, Sikora A, Heavner MS, Chen X, Smith SE. Optimizing Pharmacist Team-Integration for ICU patient Management (OPTIM): Rationale, study design, and methods for a multi-centered exploration of pharmacist-to-patient ratio. Crit Care Explor. 2023;5(9):e0956. https://doi.org/10.1097/cce.0000000000000956 [Original Research]. Citations: 0
  • Heavner MS, Louzon PR, Gorman EF, Landolf KM, Ventura D, Devlin JW. A rapid systematic review of pharmacologic sleep promotion modalities in the intensive care unit. J Intens Care Med. 2023;39(1): 28-43. https://doi:10.1177/08850666231186747 [Review]. Citations: 0
  • Howell A*, Seung H, So J, Ahmed N*, Schuchardt J*, Wilburn B*, Heavner MS. Nighttime medication administration and patient perception of sleep in the intensive care unit. J Am Coll Clin Pharm. 2023;6(8):880-888. https://doi.org/10.1002/jac5.1795 [Original research]. Citations: 1
  • Heavner MS, Erdman G*, Barlow B, Aldhaeefi M, Cucci M, Eng C, Hawkins WA, Rose C, Smith S, Magee C, Lankford A, Li M, Bastin MT. Caring for two in the ICU: pharmacotherapy in the critically ill pregnant patient. 2023;43(5):403-418. https://doi.org/10.1002/phar.2795 [Invited Review]. Citations: 0
  • Heavner MS, Cucci M, Barlow B, Magee C, Erdman G*, Li M, Smith S, Aldhaeefi M, Bastin MT, Eng C, Hawkins WA, Rose C, Lankford A. Caring for two in the ICU: pharmacologic management of pregnancy-related complications. 2023; 3(7):659-674. https://doi.org/10.1002/phar.2837 [Invited Review]. Citations: 1
  • Chang CWJ, Provencio JJ, Pascual J, Heavner M, Olson M, Livesay S, Kaplan LJ. State-of-the-art evaluation of acute adult disorders of consciousness for the general intensivist. Critical Care Medicine. 2023;51(7):948-963. https://doi.org/10.1097/ccm.0000000000005893 [Invited Review]. Citations: 4
  • Knauert MP, Ayas NT, Bosma, KJ, Drouot X, Heavner MS, Owens RL, Watson PL, Wilcox ME, Anderson BJ, Cordoza ML, Devlin JW, Elliott R, Gehlbach BK, Girard TD, Kamdar BB, Korwin AS, Lusczek ER, Parthasarathy S, Spies C, Sunderram J, Telias I, Weinhouse GL, Zee PC. Causes, consequences, and treatments of sleep and circadian disruption in the intensive care unit: An official American Thoracic Society research statement. Am J Respir Crit Care Med. 2023;207(7):e49-e68. https://doi.org/10.1164/rccm.202301-0184st [Invited Research Statement]. Citations: 18
  • Barlow B, Landolf K, LaPlante R*, Cercone J*, Kim J-Yeon*, Ghorashi S*, Howell A*, Armahizer M, Heavner MS. Electrolyte considerations in targeted temperature management. Am J Health Syst Pharm. 2023;80(3):102-110. https://doi.org/10.1093/ajhp/zxac307 [Review]. Citations: 1
  • Cucci M, Palm N, Vazquez D, Mullen C, Heavner MS. Survey of critical care practices for alcohol withdrawal syndrome in the intensive care unit. J Am Coll Clin Pharm. 2022; 5(9):950-958. https://doi.org/10.1002/jac5.1674 [Original Research]. Citations: 1
  • Chudow MB, Condeni MS, Dhar S, Heavner MS, Nei AM, Bissel BD. Current practice review in the management of acute respiratory distress syndrome. J Pharm Pract. 2022; 36(6):1454-1471. https://doi.org/10.1177/08971900221108713 [Review]. Citations: 1
  • Heavner MS, Gorman EF, Linn DD, Yeung SYA, Miano TA. Systematic review and meta-analysis of the correlation between bispectral index (BIS) and clinical sedation scales: towards defining the role of BIS in critically ill patients. Pharmacotherapy. 2022; 42(8):667-676. https://doi.org/10.1002/phar.2712 [Original Research]. Citations: 17
  • Sikora A, Ayyala D, Blackwell SB, Campbell J, Caylor MM, Condeni MS, DePriest A, Dzierba AL, Flannery AH, Hamilton LA, Heavner MS, Horng M, Lam J, Liang E, Montero J, Murphy D, Plewa-Rusiecki AM, Sacco AL, Sacha GL, Shah P, Smith MP, Smith Z, Radosevich JJ, Vilella AL, Rech MA. Impact of pharmacists to improve patient care in the critically ill: A large multicenter analysis using meaningful metrics. Critical Care Medicine. 2022;50(9):1318-1328. https://doi.org/10.1097/ccm.0000000000005585 [Original Research]. Citations: 25
  • Groth CM, Droege CA, Connor KA, Kaukeinen K, Acquisto NM, Chui SHJ, Cucci MD, Dixit D, Flannery AH, Gustafson KA, Glass NE, Horng H, Heavner MS, Kinney J, Kruer RM, Peppard WJ, Sarangarm P, Sikora A, Viswesh V, Erstad BL. Multicenter retrospective review of ketamine use in the ICU. Crit Care Explor. 2022; 4(2):e0633. https://doi.org/10.1097/cce.0000000000000633 [Original Research]. Citations: 12
  • Bissell BD, Johnston JP, Smith RR, Newsome AS, Thompson Bastin ML, Abdul-Mutakabbir J, Barlow A, Barlow B, Berger K, Crow JR, Dixit D, Jacobi J, Karaoui LR, Kiser TH, Kolesar J, Koontz SE, Mattingly TJ, Mitchell C, Nilges A, Rech MA, Heavner MS. Gender inequity and sexual harassment in the pharmacy profession: Evidence and call to action executive summary. J Am Coll Clin Pharm. 2021; 4(11):1375-1378. https://doi.org/10.1002/jac5.1508 [Review]. Citations: 2
  • Landolf K, Lemieux S, Rose C, Johnston J, Adams C, Altshuler J, Berger K, Dixit D, Effendi M, Heavner MS, Lemieux D, Littlefield A, Nei A, Owusu K, Rinehart M*, Robbins B, Rouse G, Thompson Bastin M. Corticosteroid use in ARDS and its application to evolving therapeutics for Coronavirus Disease 2019 (COVID-19): a systematic review. Pharmacotherapy. 2022; 42(1):71-90. https://doi.org/10.1002/phar.2637 [Review]. Citations: 17
  • Louzon PR, Heavner MS, Herod K, Wu TT, Devlin JW. Sleep-promotion bundle development, implementation, and evaluation in critically ill adults: roles for pharmacists. Annals of Pharmacotherapy. 2022; 56(7):839-849. https://doi.org/10.1177/10600280211048494 [Review]. Citations: 12
  • Eng CC, Heavner MS. Pharmacology Considerations in Women. Clin Chest Med. 2021; 42(3):557-566. https://doi.org/10.1016/j.ccm.2021.04.013 [Review]. Citations: 1
  • Bissell BD, Johnston JP, Smith RR, Newsome AS, Thompson Bastin ML, Abdul-Mutakabbir J, Barlow A, Barlow B, Berger K, Crow JR, Dixit D, Jacobi J, Karaoui LR, Kiser TH, Kolesar J, Koontz SE, Mattingly TJ, Mitchell C, Nilges A, Rech MA, Heavner MS. Gender inequity and sexual harassment in the pharmacy profession: Evidence and call to action. Am J Health Syst Pharm. 2021; 78(22):2059-2076. https://doi.org/10.1093/ajhp/zxab275 [Review]. Citations: 28
  • Johnston JP*, Heavner MS, Liu MH, Casal GC*, Akgun K. The prevalence of drug-drug interactions with antiretroviral therapy in human immunodeficiency virus-infected patients in the intensive care unit. J Pharm Pract. 2021; 36(2):322-328. https://doi.org/10.1177/08971900211035262 [Original Research]. Citations: 5
  • Kalaria S, Williford S*, Guo D, Shu Y, Medlin C*, Li M*, Yeung SYA, Ali F, Jean W, Gopalakrishnan M, Heavner MS. Optimizing ceftaroline dosing in critically ill patients undergoing continuous renal replacement therapy. Pharmacotherapy. 2021; 41(2):205-211. https://doi.org/10.1002/phar.2502 [Original Research]. Citations: 11
  • Blanco N, Robinson GL, Heil EL, Perlmutter R, Wilson LE, Brown CH, Heavner MS, Nadimpalli G, Lemkin D, Morgan DJ, Leekha S. Impact of a C. difficile infection (CDI) reduction bundle and its components on CDI diagnosis and prevention. American Journal of Infection Control. 2021; 49(3):319-326. https://doi.org/10.1016/j.ajic.2020.10.020 [Original Research]. Citations: 6
  • Bastin MT, Berger K, Adams C, Altshuler J, Dixit D, Effendi M, Johnston J, Lemieux D, Lemieux S, Littlefield A, Owusu K, Rose C, Rouse G, Heavner MS. Adapting clinical pharmacy staffing models during the COVID-19 pandemic: lessons learned and considerations for future disaster planning. J Am Coll Clin Pharm. 2020; 4(1):10-19. https://doi.org/10.1002/jac5.1374 [Original Research]. Citations: 4
  • Adams C, Altshuler J, Barlow B, Dixit D, Droege C, Effendi M, Heavner MS, Johnston J, Kiskaddon A, Lemieux D, Lemieux S, Littlefield A, Owusu K, Rouse G, Thompson Bastin M, Berger K. Analgesia and sedation strategies in mechanically ventilated adults with COVID-19. Pharmacotherapy. 2020; 40(12):1180-1191. https://doi.org/10.1002/phar.2471 [Review]. Citations: 38
  • Owusu KA, Kurczewski L, Armahizer MJ, Zichichi A, Maciel C, Heavner MS. DEXmedetomidine compared to PROpofol in NEurocritical Care [DEXPRONE]: A multicenter retrospective evaluation of clinical utility and safety. J Crit Care. 2020; 60:79-83. https://doi.org/10.1016/j.jcrc.2020.07.021 [Original Research]. Citations: 12
  • Roberts RJ, Miano TA, Hammond DA, Patel GP, Chen JT, Phillips KM, Lopez N, Kashani K, Qadir N, Cairns CB, Mathews K, Park P, Khan A, Gilmore JF, Brown ART, Tsuei B, Handzel M, Chang AL, Duggal A, Lanspa M, Herbert JT, Martinez A, Tonna J, Ammar MA, Nazer LH, Heavner MS, Pender E, Chambers L, Kenes MT, Kaufman D, Downey A, Brown B, Chaykosky D, Wolff A, Smith M, Nault K, Gong M, Sevransky JE, Lat I. Evaluation of vasopressor exposure and mortality in patients with septic shock. Crit Care Med. 2020; 48(10):1445-1453. https://doi.org/10.1097/ccm.0000000000004476 [Original Research]. Citations: 44
  • Chen JT, Roberts R, Fazzari MJ, Kashani K, Qadir N, Cairns CB, Mathews K, Park P, Khan A, Gilmore JF, Brown ART, Tsuei B, Handzel M, Chang L, Duggal A, Lanspa M, Herbert JT, Martinez A, Tonna J, Ammar MA, Hammond D, Nazer LH, Heavner MS, Pender E, Chambers L, Kenes MT, Kaufman D, Downey A, Brown B, Chaykosky D, Wolff A, Smith M, Nault K, Sevransky J, Gong MN. Variation in fluid and vasopressor use in shock with and without physiologic assessment: a multicenter observational study. Crit Care Med. 2020; 48(10):1436-1444. https://doi.org/10.1097/ccm.0000000000004429 [Original Research]. Citations: 9
  • Witcraft EJ*, Gonzales JP, Seung H, Watt I, Tata AL, Yeung SY, Heavner MS, Qato DM, Gulati MS, Millstein LS. Continuation of opioid therapy at transitions of care in critically ill patients. J Intens Care Med. 2020; epub ahead of print. https://doi.org/10.1177/0885066620933798 [Original Research]. Citations: 9
  • Barlow B*, Barlow A*, Bastin MLT, Berger K, Dixit D, Heavner MS. Minimizing pharmacotherapy-related healthcare worker exposure to SARS-CoV-2. Am J Health Syst Pharm. 2020; 77(18): 1529-1531. https://doi.org/10.1093/ajhp/zxaa190 [Review]. Citations: 1
  • Hsu G*, Gonzales JP, Seung H, Heavner MS, Jean W, Shah NG. Antimicrobial therapy in septic shock is conservative during resuscitation and maintenance phases. J Pharm Technol. 2020; 36(4):119-125. https://doi.org/10.1177%2F8755122520921516 [Original Research]. Citations: 2
  • Barlow A*, Landolf KM*, Barlow B*, Yeung SYA, Heavner JJ, Claassen CW, Heavner MS. Review of emerging pharmacotherapy for the treatment of coronavirus disease 2019. Pharmacotherapy. 2020; 40(5):416–437. https://doi.org/10.1002/phar.2398 [Invited Review]. Citations: 297
  • Boyce EG, Harris CS, Bingham AL, Chan E, Chapman SA, Chilbert MR, Dy-Boarman E, Haines ST, Heavner MS, Marcus KB, Smith SE, Strnad K, Yunker NS. ACCP White Paper: striving for excellence in experiential education. J Am Coll Clin Pharm. 2020; 3:678–691. https://doi.org/10.1002/jac5.1240 [Invited White Paper]. Citations: 19
  • Boyce EG, Harris CS, Bingham AL, Chan E, Chapman SA, Chilbert MR, Dy-Boarman E, Haines ST, Heavner MS, Marcus KB, Smith SE, Strnad K, Yunker NS. ACCP Position Paper: striving for excellence in experiential education. J Am Coll Clin Pharm. 2020; 2020;3:692–695. https://doi.org/10.1002/jac5.1241 [Invited Position Paper]. Citations: 2
  • Heavner MS, McCurdy MT, Mazzeffi MA, Galvagno SM, Tanaka KA, Chow JH. Angiotensin II and vasopressin for vasodilatory shock: a critical appraisal of catecholamine-sparing strategies. J Intens Care Med. 2020; epub ahead of print. https://doi.org/10.1177/0885066620911601 [Review]. Citations: 7
  • Armstrong F*, McCurdy M, Heavner MS. Synthetic cannabinoid-associated multiple organ failure: case series and literature review. 2019 Apr;39(4):508-513. https://doi.org/10.1002/phar.2241 [Original Research]. Citations: 41
  • Heavner MS, Nguyen NK*, Knauert MP, Verceles A, Pisani MA, Seung H, Gonzales JP. Survey of clinical pharmacist perceptions and practices in promoting sleep in intensive care unit patients. J Am Coll Clin Pharm. 2019; 2:46-52. https://doi.org/10.1002/jac5.1027 [Original Research]. Citations: 3
  • Heavner JJ, Akgun K, Heavner MS, Eng CY, Drew M*, Jackson P*, Pritchard DA*, Honiden S. Implementation of an ICU-specific alcohol withdrawal syndrome management protocol reduces the need for mechanical ventilation. 2018; 38(7):701-713. https://doi.org/10.1002/phar.2127 [Original Research]. Citations: 23
  • Littlefield AJ*, Heavner MS, Chan CY, Heavner JJ, Cooper C, Kurtz D, Pisani MA. The correlation between mMINDS and CIWA-Ar scoring tools in alcohol withdrawal patients. Am J Crit Care. 2018 Jul;27(4):280-286. https://doi.org/10.4037/ajcc2018547 [Original Research]. Citations: 20
  • Heavner MS, Masich AM*, Claeys KC, Gonzales JP. Pharmacokinetic and pharmacodynamic considerations of antibiotics of last resort in treating gram-negative infections in adult critically ill patients. Curr Infect Dis Rep. 2018 Apr;20(5). https://doi.org/10.1007/s11908-018-0614-0 [Review]. Citations: 13
  • Masich AM*, Heavner MS, Gonzales JP, Claeys KC. Pharmacokinetic/pharmacodynamic considerations of beta-lactam antibiotics in adult critically ill patients. Curr Infect Dis Rep. 2018 Apr 4;20(5):9. https://doi.org/10.1007/s11908-018-0613-1 [Review]. Citations: 36
  • Heavner MS, Rouse GE, Lemieux SL, Owusu KA, Pritchard D, Yazdi, M, Lee L. Experience with integrating pharmacist documenters on cardiac arrest teams to improve quality. J Am Pharm Assoc. 2018 May-Jun; 58(3):311-317. https://doi.org/10.1016/j.japh.2017.08.003 [Original Research]. Citations: 7
  • Heavner MS, Zhang M, Bast CE*, Parker L*, Eyler RF. Thrombolysis for massive pulmonary embolism in pregnancy. Pharmacotherapy. 2017;37(11):1449-1457. https://doi.org/10.1002/phar.2025 [Review]. Citations: 31
  • Heavner MS, Tichy EM, Yazdi M. Stepping it up: implementation of a pharmacist career ladder program. Am J Health Syst Pharm. 2016;73:1524-30. https://doi.org/10.2146/ajhp150615 [Original Research]. Citations: 14
  • Farrokh S*, Castle AC, Heavner MS, Pisani MA. Continuation rate of atypical antipsychotics after discharge when initiated in the intensive care unit. J Pharm Pract. 2016 Apr; 30(3):342-346. https://doi.org/10.1177/0897190016645026 [Original Research]. Citations: 19
  • Heavner MS, Tichy EM, Yazdi M, Formica RN, Kulkarni S, Emre S. Clinical outcomes associated with conversion from brand-name to generic tacrolimus in hospitalized kidney transplant recipients. Am J Health Syst Pharm. 2013 Sept; 70(17):1507-1512. https://doi.org/10.2146/ajhp120783 [Original Research]. Citations: 14
  • Ruggero MA*, Argento AC, Heavner MS, Topal JE. Molecular Adsorbent Recirculating System (MARS®) removal of piperacillin/tazobactam in a patient with acetaminophen-induced acute liver failure. Transpl Infect Dis. 2013 Apr; 15(2):214-218. https://doi.org/10.1111/tid.12031 [Original Research]. Citations: 15
  • Cirulli J, McMillian W, Saba M, Stenehjem D. Adaptive trial design: the future of clinical research and the impact on pharmacists. Am J Health Syst Pharm. 2011 May; 68(9):807-813. https://doi.org/10.2146/ajhp100298 [Review]. Citations: 8
  • Paul SC, Saba M, Berger K. Revisiting an old therapy: theophylline in asthma. JAEE. 2010 Oct; 1(5):180-183. https://doi.org/10.1177%2F2150129710372963 [Review]. Citations: 4
  • Mullins CD, Palumbo FB, Saba M. Formulary tier placement for commonly prescribed branded drugs: benchmarking and creation of a preferred placement index. Am J Manag Care. 2007 Jun; 13(6 part 2):377-384. https://pubmed.ncbi.nlm.nih.gov/17567239/ [Original Research]. Citations: 8

Book Chapters

  • Miklich MA, Heavner MS. “Drug-Induced Pulmonary Diseases.” In Pharmacotherapy: A Pathophysiologic Approach, edited by S.T. Haines, T.D. Nolin, and V.L. Ellingrod, 12th edition. Philadelphia, PA: McGraw-Hill Education.
  • Heavner MS, Heavner JJ. “Pain, Agitation, and Delirium in Critical Care.” In Schwinghammer TL et al, eds. Pharmacotherapy Casebook: A Patient-Focused Approach. 12th ed. New York: McGraw-Hill, 2023.
  • Heavner MS, Louzon PR. 2022. “Effects of Common ICU Medications on Sleep in the ICU.” In Sleep in Critical Illness: Physiology, Associated Outcomes, and its Potential Role in Recovery, edited by G.L. Weinhouse and J.W. Devlin. Springer Nature.
  • Heavner JJ, Saba M. “Adverse drug interactions.” In Yale Office-based Medicine Curriculum, edited by J. Rosenbaum, S. Hay, L. Whitman, M. Warner, 7th edition. New Haven, CT: Yale University.