Selected Publications

  1. Salem AM, Niu T, Li C, Moffett BS, Ivaturi V, Gopalakrishnan M. Reassessing the Pediatric Dosing Recommendations for Unfractionated Heparin Using Real-World Data: A Pharmacokinetic-Pharmacodynamic Modeling Approach. J Clin Pharmacol. Published online November 23, 2021. PMID: 34816442
  2. Wijekoon N, Aduroja O, Biggs JM, El‐Metwally D, Gopalakrishnan M. Model‐Based Approach to Improve Clinical Outcomes in Neonates With Opioid Withdrawal Syndrome Using Real‐World Data. Clin Pharmacol Ther. 2021;109(1):243-252
  3. Kalaria SN, Armahizer M, McCarthy P, Badjatia N, Gobburu JV, Gopalakrishnan M. A Practice-Based, Clinical Pharmacokinetic Study to Inform Levetiracetam Dosing in Critically Ill Patients Undergoing Continuous Venovenous Hemofiltration (PADRE-01). Clin Transl Sci. 2020;13(5):950-959
  4. Kalaria SN, Gopalakrishnan M, Heil EL. A Population Pharmacokinetics and Pharmacodynamic Approach To Optimize Tazobactam Activity in Critically Ill Patients. Antimicrob Agents Chemother. 2020;64(3): e02093-19
  5. Gopalakrishnan M, Zhu H, Farchione TR, et al. The Trend of Increasing Placebo Response and Decreasing Treatment Effect in Schizophrenia Trials Continues: An Update from the US Food and Drug Administration. J Clin Psychiatry. 2020;81(2). PMID: 3214172.

Complete List of Published Work in MyBibliography


  • Validation of Surrogate Endpoints by Bayesian Equivalence testing.  Mathangi Gopalakrishnan, Anindya Roy, Thomas Mathew.
    Oral Poster presentation at Joint Statistical Meetings (JSM), at SanDiego, July-August 2012 and American Conference on Pharmacometrics (ACoP) at Ft.Lauderdale, May 2013.
  • Non-iterative Bayesian Sampling for analyzing Zero-Inflated Count Data. Mathangi Gopalakrishnan, Guo-Liang Tian, Ming Tan.
    Poster presentation at Workshop on Contemporary Statistical Methods in Biostatistics, UMBC, Baltimore, MD, March,2011.
  • A Pharmacokinetic-Pharmacodynamic model for insulin to guide in optimal drug delivery. Mathangi Gopalakrishnan, Joga Gobburu.
    Poster podium presented at American Association of Pharmaceutical Scientists (AAPS), 2004 Session: Maximizing the Impact of Population PK/PD Modeling and Simulation on Drug Development Decisions, Baltimore, Maryland.
  • A Web-based Pharmacometrics learning resource. Mathangi Gopalakrishnan, Pravin Jadhav and Joga Gobburu.
    Poster presented at American College of Clinical Pharmacology (ACCP), 2004 at Phoenix, Arizona