Selected Publications
- Gopalakrishnan M, Amaria RN. Project Optimus Elicits the “Holistic” Benefits of PK/PD Modeling of Immunotherapy. Clin Cancer Res 2024;30:2862–4. https://doi.org/10.1158/1078-0432.CCR-24-0553
- Chamzas A, Tellez E, SyBing A, Gobburu JVS, Gopalakrishnan M. Optimizing tacrolimus dosing in Hispanic renal transplant patients: insights from real-world data. Front Pharmacol. 2024 Sep 19;15:1443988. doi: 10.3389/fphar.2024.1443988. PMID: 39364052; PMCID: PMC11446860.
- Shenkoya B, Gopalakrishnan M, Eke AC. Physiologically based pharmacokinetic modeling of long-acting extended-release naltrexone in pregnant women with opioid use disorder. CPT Pharmacometrics Syst Pharmacol. 2024 Nov;13(11):1939-1952. doi: 10.1002/psp4.13252. Epub 2024 Oct 9. PMID: 39380562; PMCID: PMC11578127.
- Langevin B, Gopalakrishnan M, Kuttamperoor J, Van Den Anker J, Murphy J, Arcaro KF, et al. The MILK study: Investigating intergenerational transmission of low-calorie sweeteners in breast milk. Contemp Clin Trials Commun 2023;36:101212. https://doi.org/10.1016/j.conctc.2023.101212.
- Langevin B, Gobburu JVS, Gopalakrishnan M. Is There a Need for a Dedicated Pharmacokinetic Trial for a Drug in Obese Populations? A Drug Prioritization Decision Tree Framework. J Clin Pharmacol 2023;63 Suppl 2:S48–64. https://doi.org/10.1002/jcph.2304.
- Salem AM, Niu T, Li C, Moffett BS, Ivaturi V, Gopalakrishnan M. Reassessing the Pediatric Dosing Recommendations for Unfractionated Heparin Using Real-World Data: A Pharmacokinetic-Pharmacodynamic Modeling Approach. J Clin Pharmacol. Published online November 23, 2021. PMID: 34816442
- Wijekoon N, Aduroja O, Biggs JM, El‐Metwally D, Gopalakrishnan M. Model‐Based Approach to Improve Clinical Outcomes in Neonates With Opioid Withdrawal Syndrome Using Real‐World Data. Clin Pharmacol Ther. 2021;109(1):243-252
- Kalaria SN, Armahizer M, McCarthy P, Badjatia N, Gobburu JV, Gopalakrishnan M. A Practice-Based, Clinical Pharmacokinetic Study to Inform Levetiracetam Dosing in Critically Ill Patients Undergoing Continuous Venovenous Hemofiltration (PADRE-01). Clin Transl Sci. 2020;13(5):950-959
- Kalaria SN, Gopalakrishnan M, Heil EL. A Population Pharmacokinetics and Pharmacodynamic Approach To Optimize Tazobactam Activity in Critically Ill Patients. Antimicrob Agents Chemother. 2020;64(3): e02093-19
- Gopalakrishnan M, Zhu H, Farchione TR, et al. The Trend of Increasing Placebo Response and Decreasing Treatment Effect in Schizophrenia Trials Continues: An Update from the US Food and Drug Administration. J Clin Psychiatry. 2020;81(2). PMID: 3214172.
Complete List of Published Work in MyBibliography
Recent Presentations at Conferences
- Athanasios Chamzas, Kannan Sridharan, Mathangi Gopalakrishnan. Patent Ductus Arteriosus in Preterm Infants: Exploring Optimal Acetaminophen Dosing for Oral and Rectal Administration. American Conference on Pharmacometrics (ACoP), Phoenix, Arizona, November 2024.
- Sooyoung Lee, Mathangi Gopalakrishnan. Exploring Appropriate Prior Distributions for Covariance Matrix Estimation in Bayesian Population Pharmacokinetic Analysis. American Conference on Pharmacometrics (ACoP), Phoenix, Arizona, November 2024. Trainee Quality Award Winner.
- K V. Tobin, Bianca Reginauld, Audra L. Stinchcomb, Mathangi Gopalakrishnan. Flux-based IVIVC for predicting oxybutynin exposure with and without occlusion of a transdermal gel. American Conference on Pharmacometrics (ACoP), Phoenix, Arizona, November 2024.
- Babajide Shenkoya, Ahizechukwu Eke, Mathangi Gopalakrishnan. Pharmacokinetics of Long-Acting Naltrexone in Pregnancy: Insights from Physiologically Based Pharmacokinetic Modeling. American Conference on Pharmacometrics (ACoP), Phoenix, Arizona, November 2024.
- Athanasios Chamzas, Mathangi Gopalakrishnan, Osward M. Nyirenda, Nginache Nampota-Nkomba, Jane Mallewa, Rana Rais, Jesse Alt, Matthew Laurens, Douglas G. Postels, Brittany A. Riggle. American College of Clinical Pharmacology (ACCP), Bethesda, MD. September 2024.