Daniel J. Deredge, PhD, is an assistant professor in the Department of Pharmaceutical Sciences at the University of Maryland School of Pharmacy.
Daniel J. Deredge, PhD
Assistant Professor, Department of Pharmaceutical Sciences
University of Maryland School of Pharmacy
20 North Pine Street, Room N529
Baltimore, MD 21201
Office: 410-706-2096
Email: dderedge@rx.umaryland.edu
Lab website
Postdoctoral – Accepting applicants
PhD (Fall 2023) – Currently recruiting
MS (Fall 2023) – Currently recruiting
About Dr. Deredge:
Dr. Deredge received his PhD in biochemistry from Louisiana State University, studying DNA binding properties of bacterial DNA polymerases. His postdoctoral training was in structural mass spectrometry at Case Western Reserve University, applying Hydrogen-Deuterium exchange mass spectrometry (HDX-MS) to HIV reverse transcriptase. At the School of Pharmacy, Dr. Deredge expanded the application of HDX-MS and other structural MS methods to a multitude of systems, including viral RNA polymerases, bacterial heme uptake protein or neurotransmitter:sodium symporter, and integrating it with computational methods.
Education
- Postdoctoral, Pharmaceutical Sciences, University of Maryland School of Pharmacy
- Postdoctoral, Biophysics and Physiology, Case Western Reserve University
- PhD, Biochemistry, Louisiana State University
- BS, Biochemistry, Louisiana State University
Research Interests
The research interest in the Deredge lab focuses on the application of structural protein mass spectrometry tools integrated with computational chemistry approaches to address biophysical questions.
Current Projects
- Integrating HDX-MS Solution Data and Computational HDX Modeling to Refine Molecular Dynamics Ensembles.
- Insight into the Structure and Dynamics of the Dengue virus Nonstructural 5 (NS5) Protein.
- Optimizing protein therapeutics formulation.
For more detailed information, check out https://deredgelab.com/current-research/