Current Lab Members:

Linhao Li Ph.D. Linhao Li Ph.D. Research Associate

Linhao possesses the background spanning 5 years of pharmacology for his Ph.D. and working at the University of Maryland School of Pharmacy more than 15 years in the field of regulation of drug metabolizing enzymes and drug transporters by orphan nuclear receptors in drug metabolism and diseases.

 Zhihui Li, PhD Zhihui Li Ph.D. Postdoctoral Scientist

Dr. Zhihui Li has worked on elucidating the regulation and function of solute carrier family 13 member 5 (SLC13A5) in human liver and has published research article indicated that silencing of SLC13A5 disrupts energy homeostasis and inhibits proliferation of human hepatocarcinoma cells. Additional research interests are centered on the biological function of constitutive androstane receptor (CAR) in hepatocellular carcinoma (HCC). His research results suggest that human CAR plays a tumor suppressive role in HCC development which differs from that of rodent CAR and offers insight into the hCAR-HNF4α-EPO axis in human liver tumorigenesis

Kaiyan Liu Ph.D. Postdoctoral Scientist

Kaiyan is working on a project supported by Food and Drug Administration, this program mainly focuses on Drug-induced liver injury, Drug-induced liver injury represents the primary cause of drug attrition during development and post-marketing. In this project, we will investigate potential metabolism-based drug-drug interactions (DDI), and human liver toxicity of drugs used for COVID-19 treatment and other viruses, using the state-of-art 3D human liver spheroid model. The success of the proposed research will provide important human-relevant data that could eventually improve the therapeutic safety and efficacy of drugs for COVID-19 and other viruses infection.

  Ritika Kurian, Graduate Student

Ritika Kurian is a graduate student who has completed her masters in pharmaceutical sciences from Northeastern University. The emphasis of her research is to explore the utilization of an adjuvant drug to increase metabolic bioactivation of cyclophosphamide by employing advanced techniques such as liquid chromatography-tandem mass spectrometry in addition to cell and animal-based approaches.

 
 

 

Former Lab Members:

Sydney Stern Ph.D, (graduate student, 2017-2022) Current position: Scientist, CEDR, FDA, Silver Spring, MD
Tao Hu Tao Hu Ph.D, (postdoctoral scientist, 2017-2019) Current position: Director of Pharmacology, Evergreen Therapeutics, Bethesda, MD
Bryan Mackowiak Bryan Mackowiak Ph.D, (graduate student, 2014-2019) Current position: Postdoctoral Fellow, NIAAA, NIH, Rockville.
William Hedrich Ph.D, (graduate student, 2013-2018) Current position: Research Scientist, Bristol-Myers Squibb, Princeton, NJ
Brandy Garzel Ph.D, (graduate student, 2012-2017) Current position: Research Scientist, Becton Dickinson, Sparks, MD
Yuanfu Lu Yuanfu Lu Ph.D, (visiting professor, 2017) Current position: Professor and Vice Head of Key Lab. for Basic Pharmacology of Ministry of Education, Zunyi Medical University, China
Xiumei Xin Ph.D, (postdoctoral scientist, 2015-2016) Current position: Research Associate, Sun Yat-sen University, Guangzhou, China
Daochuan Li Ph.D. (postdoctoral scientist, 2014-2016) Current position: Assistant Professor, Sun Yat-sen University, Guangzhou, China
Jingwei Xiao Ph.D. (postdoctoral scientist, 2014-2015) Current position: Research Scientist, Institute of Occupational Health, Chinese Center for Disease Control and Prevention, Beijing, China
Caitlin Lynch Ph.D. (graduate student, 2009-2014) Current position: Research Fellow, NCATS, NIH, Rockville.
Hui Yang Ph.D. (postdoctoral scientist, 2012-2014) Current position: Research Scientist, Institute of Nutrition and Food Safety, Chinese Center for Disease Control and Prevention, Beijing, China
Lan Fan Ph.D. (visiting scholar, 2014) Current position: Associate Professor, Institute of Clinical Pharmacology, Central South University, Changsha, China
Duan Wang Ph.D. (graduate student, 2008-2013) Current position: Senior Scientist at Corning Incorporated, Boston.
Leslie Tompkins Ph.D. (postdoctoral scientist, 2008-2010) Current position: Policy Analyst at FDA, Silver Spring.
Haishan Li Ph.D. (postdoctoral scientist, 2007-2010) Current position: Associate Director, Research Center for Import-Export Chemicals Safety, AQSIQ, Chinese Academy of Inspection and Quarantine.
Antonia T. Baaqee Ph.D. (graduate student, 2007-2012) Current position: Chemical Engineer at FDA, Silver Spring.
Tao Chen MD. (lab technician, 2006-2010) Current position: Postdoctoral fellow at Penn State University